Index
1. Side effects of Statins: Lipitor, Zocor, Pravachol, Mevacor Functions and Introduction.
2. HMG-CoA reductase inhibitors (statins) block CoQ-10 synthesis How statins work.
3. Questioning the premise lowering the cholesterol level is beneficial Flawed statistical premise.
4. Statins are not a safe way to lower cholesterol because They cause mitochondrial dysfunctions, myopathies, dementia, faster aging, early death, etc.
5.
KFP Hypothesis/Prediction: The cholesterol
goal is set to an unsafe level
Why prescribing is flawed.
6.
Serious questions that should not be ignored Questions and answers.
7.
What the Lipitor Patent tells us: Co-administer CoQ10 (Ubiquinol)
Important prescribing rules too frequently ignored in practice.
8.
Dr. Mercola: Summary of Key Ideas Presented Authoritative summary of statins over-dosage
situation.
9.
Statins Side Effects:
Changes cholesterol balance; higher
Ascorbic Acid (AA) need; CoQ-10 starvation
10.
Low CoQ-10 leads to high aging rates of all cell types Dr Graveline’s book.
11.
See John Ely’s papers Orthomolecular medicine,
hyperglycemia, AA, CoQ10, Pauling’s HD nutrition protocol, nutrition reverses
aging, unprofitable modalities…
12.
References
Orthomolecular Nutrition for Heart Disease improves patient heath;
statins make health worse.
13.
Dr
Whitaker’s Recommendations Where to find reports of
statin adverse drug reactions and symptoms.
14.
Important Overview of the Harmful Statin
Biochemistry and Increased Nutrient Needs
15. Scientific
American: It's Not Dementia,
It's Your Heart Medication: Cholesterol Drugs and
Memory .
16.
KFP: Flawed Statistical Marketing Studies vs.
14,000 Anecdotal Case Histories
Drug AERS under reporting.
17.
A Well-Documented Analysis of 351
Statin Adverse Case Histories A
Pareto analysis report of types of harm vs. frequency.
18.
Lipitor Side Effects Response to a Web Inquiry
19.
Statin
Cholesterol Lowering Drugs have the following characteristics: -Fonorow
Long list.
20.
Defenses
against Statins side effects: AA and CoQ10 and Lysine
21.
More
headlines from illustrate the health benefits of Vitamin C: Long list.
22.
Fonorow’s
Conclusions [with our comments]
23. According to Dr. Langsjoen, Testamonial Greatly increased heart myopathies and
dementia in patients taking statins.
24.
Our Conclusion: Medical costs explosion is because we are not
using orthomolecular medicine and nutrition.
Side effects of Statins:
Lipitor, Zocor, Pravachol, Mevacor, and other cholesterol-lowering
statin drugs.
Generic
Names: lovastatin,, atorfastatin, rosuvastatin, fluvastatin, pravastatin,
imvastatin, ezetimbe/simvastatin.
(Sometimes with niacin)
The purpose of statin drugs is to manage the blood levels
of cholesterols to change the patients’ test results so that they test in a
percentile group of previously studied different patients that had a
statistically lower level of heart attack deaths. The underlying known disease and nutritional factors in heart
disease were not accounted for or were presumably randomized. Test related management rather than health
related nutritional improvements.
Nutritional improvement has much better results in improving patients’
health. Statin use causes cardio
myopathy, nerve degeneration and accelerated aging.
The studies of statin use side effects are now becoming
evident and are described in later sections.
They are not nice.
HMG-CoA reductase inhibitors (statins) block CoQ-10 synthesis. [Google: mevalonate pathway]
· CoQ10 is essential to life, cellular energy release, mitochondrial health.
·
CoQ10
deficiencies increase the rates of aging.
·
CoQ10
need is ~ 500 mg/day; amount made in liver is decreased by >50% or more
depending on dosage of statins.
·
CoQ10
in food is 5-10 mg per day; supplements are needed after age 40.
·
CoQ10
supplementation will reverse only some of the statins’ side effects.
·
Too
low cholesterol causes neuropathy and degenerative changes in muscles and
nerves.
Questioning
the premise: lowering the cholesterol level is beneficial: False
Since statins cause toxins it is equivalent
to the premise: toxins are safe. Obviously
False.
We make the proper cholesterol we need in the liver,
if we do not block the process.
Highest cholesterol group 98.7%.
Lowest cholesterol group 99.7%.
·
Problems
with statistics: presentation of selected “facts” to prove desired result
Not distinguishing between eaten- and made-
cholesterols or molecule shapes.
Gee Whiz! Statistics: .3% vs. 1.3% is over a 300%
improvement.
Not a before vs. after example. (see Langsjoen,
cardio myopathies are increased)
Permits selling “dubious security” to large number
of persons, based on pathology of a few.
Marketing is highly profitable to makers and
sellers.
Increases in other health death rates and misery
index statistics not accounted for.
Statins are not a safe way to lower cholesterol because:
This advances aging causes lack of vigor,
mitochondrial dysfunction.
Chronic infections and Mitochondrial dysfunctions causal factor in adverse vaccine reactions.
KFP
Hypothesis/Prediction: The cholesterol goal is set to an unsafe level
If
there is a predisposition for a mental/neural dysfunction (ALS/Alzheimer’s/Parkinson’s)
then statins will accelerate symptoms.
Serious
questions that should not be ignored:
1.
Heme
A is essential for mitochondrial energy flow in the cells. Antioxidant: It
protects against DNA damage.
2.
CoQ10
is essential for mitochondrial energy flow in the cells. It is also a
protective antioxidant. Needed to keep cell-division errors low.
3.
If
1 & 2 are missing or too low we have mitochondrial dysfunction, muscle
pain, neural dysfunctions, and atrophies.
4.
If
1 &2 are too low we have DNA damage leading to cell death or replication
errors. Aging is advanced; vitamin C helps.
5.
What
are the functions of: a) Dolichols, b) Prenylated Proteins? Google them to see.
6.
What
are the various harms of 5 a) & 5 b) being too low. Google to see.
7.
We explore the harmful functional effects of low cholesterol and
low ubiquinone (CoQ10) in the following pages.
What the Lipitor Patent tells us: Co-administer CoQ10 (Ubiquinol)
The
Lipitor patent describes the need for high levels [> 300 mg /day] of CoQ10 to be co-administered with Lipitor to
avoid harm.
Medical
practitioners are not told to do this so they too often do not treat the
patient properly.
The
result is higher rates of side effects than were shown in the earlier
lower-dosage-level published studies.
The
deficiencies in Heme A, Prenylated proteins, and Dolichols are not fixed by
restoring CoQ10.
Thus
we have a fix for only 1/5th of the malnutrition caused by statins,
terrible!
Dr. Mercola: Summary of Key Ideas Presented.
1.
The
odds are greater than 100 to 1 that if you're taking a statin, you don't really
need it.
2.
Cholesterol
is NOT the cause of heart disease. Scurvy is the cause. Cure is Ascorbic acid,
Vitamins, CoQ10, Lysine, Proline, See Pauling
3.
Your
body NEEDS cholesterol—it is important in the production of cell membranes,
hormones, vitamin D and bile acids that help you to digest fat. Cholesterol
also helps your brain form memories and is vital to your neurological function.
4.
There is also strong evidence that having too
little cholesterol INCREASES your risk for cancer, memory loss,
Parkinson's disease, hormonal imbalances, stroke, depression, suicide, and
violent behavior.
5.
[If you already have these problems you should not take statins. Should
not lower cholesterol. Take Lovaza and see if it helps.]
6. The ONLY subgroup that benefits from statins has a genetic defect called familial hypercholesterolemia, that makes them resistant to traditional ways to normalizing cholesterol.”
9.
Current
Cholesterol levels goals:
10.
Better
ways to lower cholesterol than taking statins if you must lower it.
11.
Lovaza:
EPA&DHA ethyl esters of Omega-3 oils is a
prescription form of EPA & DHA from fish oil.
[insert]
= KFP comments or insertion of related information.
Statins
Side Effects: Changes cholesterol balance,
lower Ascorbic Acid (AA), and CoQ-10 starvation. [Toxins
&oxides proliferate]
Low/oxidized
cholesterol harms myelin sheaths of nerves, systemically.
12.
Systemic
energy lowered; Chronic fatigue symptoms worse.
13.
Does
not stop heart and circulatory damage; Post mortem plaques much worse than for
those not taking statins.
14.
Mitochondrial
DNA damage and dysfunctions; increases sensitivity to vaccine adverse effects;
increase need for vitamins E and C.
15. Immune system (T-cell) dysfunctions result increased re-activation of chronic persistent parasitic microbes (bacteria, yeasts, viruses, protozoa).
16.
Cataracts
and other low vitamin C effects due to AA depletion in lenses and borderline
scurvy. AA consumption rate is much higher.
17.
COPD
worsens long term [interstitial pneumonitis];
18. Low-cholesterol dysfunctions: sex hormone production, hair loss, sleep problems, or improper brain and
nerve functions.
19.
Muscle
pains, weakness and atrophy (Rhabdomyolysis); loss of endurance, balance
problems. Very high incidence of myopathy symptoms
20.
Muscle
and nerve pains cause less exercise, weight gain, less lymph flow and related
pathologies.
21.
Pancreas
or liver dysfunction; including a potential increase in harmful liver enzymes;
liver toxicity; enzyme test shows destruction.
22.
Kidney
functions impaired; Osteoporosis/bone health worsening.
23.
Acidosis;
Anemia; Sexual dysfunctions. CoQ10 low-level linkage.
24.
ALS-like
symptoms due to low systemic cholesterol; Study: remarkable increases in ALS
symptoms, diagnosis rates.
25.
Memory
functions lost: Short-term forgetfulness, lack of focus, mental slowness; brain
fog, loss of attention.
26.
Increased
suicide rates; “bad thoughts”; depression; aggression.
27.
Parkinson’s
symptoms start/increase; Alzheimer’s mental decline accelerates.
28.
Sudden
total loss of recent memory [TGA] transient global amnesia. [very rare, but
significantly higher in study]
29.
Heart
functions lessened; too low blood pressure; less blood flow to brain, muscles
and kidneys.
Source:
Adverse Events of
Statins - An Informal Internet-based Study
Low
CoQ-10 leads to high aging rates of all cell types:
Dr Graveline: Duane Graveline, MD, MPH
See my books: The
Dark Side of Statins & The Statin Damage Crisis.
1.
Mitochondrial DNA damage and mutation, primary factors in how we age.
2.
ROS and NOS in the presence of low ascorbic acid levels causes systemic scurvy.
3.
Resulting in systemic degeneration and atrophies in muscles and nerves.
See John
Ely’s papers: CoQ10 and Ascorbic Acid
John
Ely: Coq10 Update JOM5.html John
Ely Science of Essential Nutrition
“Unprofitable Modalities” CoQ10
Turnover
References:
· Statin Effects Study, headed by Dr. Golomb of the University of California, San Diego, 4,000 reports of cognitive dysfunction—were diagnosed as rapidly progressing Alzheimer’s disease. Much on too low cholesterol vs. brain functions.
· http://www.virginiahopkinstestkits.com/whitakerstatins.html [The] “brain contains an abundance of cholesterol, much of it in the myelin sheaths that insulate the neurons and speed up nerve conduction. Recent research reveals that cholesterol is also required for the formation of synapses, the areas between neurons where nerve impulses are transmitted and received. In fact, cholesterol is so important that it is manufactured by the glial cells in the supportive tissues of the brain.
·
Dr Whitaker: No
statin studies show benefits for women. The largest randomized clinical trial
of statins in women found Lipitor group had 10 percent more heart attacks than
placebo. No research showing any statins-extended life for anyone over
age 70. [Translation: statins
hasten end of life, via enhanced scurvy.]
Orthomolecular Nutrition for
Heart Disease:
Dr Whitaker’s Recommendations: Where to find reports of statin adverse drug reactions and
symptoms oriented websites.
Dr Whitaker’s References
Important Overview
of the Harmful Statin Biochemistry and Increased Nutrient Needs:
CoQ10 and Statins: The Vitamin
C Connection by Owen R. Fonorow
� 2003
We are now in a position to witness the unfolding of the greatest
medical tragedy of all time - never before in history has the medical
establishment knowingly created a life threatening nutrient deficiency in
millions of otherwise healthy people. --Peter H.
Langsjoen, MD
The following claim from one … 1990 Merck patent (4,933,165) is to
add CoQ10 to statin drugs in order to overcome statin induced
myopathy: [Not to mention all the
various neuropathies]
“1. A pharmaceutical
composition comprising a pharmaceutical carrier and an effective
antihypercholesterolemic amount of an HMG-CoA reductase inhibitor and an
amount of Coenzyme Q.sub.10 [CoQ10] effective to counteract HMG-CoA reductase inhibitor-associated skeletal muscle
myopathy.”
[And all the other harm caused by low blood level CoQ10 caused,
see the above list of “Side Effects:”]
Fonorow Quote:
“This invention has never been [properly] implemented, probably
because the entire world supply of CoQ10 is limited and current production
would only supply one-sixth of the world’s statin users.”
Scientific American: It's Not Dementia, It's Your Heart
Medication: Cholesterol Drugs and Memory
Two readers’ comments are notable:
1)
Lovaza:
DHA&EPA ethyl esters of Omega-3 oils aids recovery of mental acuity & speed.
2)
Statin
Side effects of HMG-CoA reductase
inhibitors in the mevalonate pathway:
o Empirically speaking, HMG-CoA reductase inhibitors (statins) are creating a problem for many of the people taking them. In a recent informal internet-based collection of self-reported data, from the users of statins or their caretakers, the incidence of Amyotrophic Lateral Sclerosis aka motor neuron disease (Lou Gehrig's disease) and other significant major neurological disturbances was remarkable.
o
The
incidence of ALS is put at 1:200,000 people in the USA and in 351 reports there
were 19 reports of ALS/MND. On the current incidence statistics, I should have
seen more than 3.6 million reports before seeing 19 cases of ALS.
o
Interested
parties can read the informal report (published by the journal of independent
medical research) and see precisely what information which was self-reported;
at the following URL: http://www.joimr.org/JOIMR_Vol7_No1_Dec2009.pdf
o There were a further 8 cases of Parkinson's disease and single occurrences of CIDP, Alzheimer's disease, and Progressive supra-nuclear palsy. In all, there were 29 reports of major progressive neurological dysfunction. [29 out of 351]
KFP
Comments: Flawed Statistical Marketing Studies vs. Anecdotal
More
than 14,000 patient reports were collected on web, vastly more than the number
of doctors’ adverse drug reports.
Patients report their doctors deny any chance of harm from statins and
refuse to link their own side effects to statin drugs. Doctors appear brainwashed by all the
positive ‘educational’ propaganda planted by the drug makers. The aggregation of so many similar anecdotal
reports of harm belies the earlier low dosage statistical studies. Also, the
known biochemistry proves multiple functional mechanisms of harm. Functional
mechanisms should trump suspect statistical and drug company supported research
studies and propaganda. However control of funding of journals and paid-for-placement
arrangements decide what the doctors
hear. The doctors are the target of the propaganda.
Many patients reported adverse symptoms on starting statins and/or reversal of some symptoms when quickly stopping statins. The biochemistry basis for the functional science is documented. If CoQ10 levels are too low, functional changes, some irreversible, lead to loss of functionality of muscles, nerves, brain functions. High levels of ascorbic acid (AA) can partly reduce the problems resulting from low CoQ10 levels. But the amounts and frequency of AA intake (10 to 20 grams/day, 12x/day) almost always are not at the levels needed to provide protection from statin dosages (10-40mg or more per day). CoQ10 supplementation helps but there are the essential Heme A and other mevalonate pathway product deficiencies that no one is addressing. These deficiencies are also critical.
Pharmacokinetics of AA has the blood half-life time as ½ hour. This means the AA concentration will be 1/8 in 1.5 hours; 1/64 in 3hours; 1/212 after 6 hours. Under statin-caused chemical stress and increased ROS/NOS the amount of AA per day may well exceed 24 grams. This is 2 grams every 2 hours. Not much if you think of AA as a food that is metabolized and quickly excreted. Some terminal conditions need 150 grams/day/100kg body weight by IV to achieve remission. Plasma concentrations need to reach the same levels that are lethal to microbes/cancer-cells in-vitro. See Cathcart: Titration to Bowel Tolerance
Many
of the symptoms of the statin reactions are the same as aging, so they are
dismissed as having no proximate cause.
Functional causes are multiply documented in the literature, but most
are unread. See John Ely’s wisdom. UofWashington:
Ely: On the Science of Essential Nutrients 2002 “Unprofitable Modalities”
Promotional statistical medicine studies are substituted for functional, biochemical science. Study reports are subject to editorial distortions that do frequently occur, because they are drug-company funded. Study or publications about adverse issues are not funded, published or promoted.
Doctors fail to recognize that when we are near death, we are dieing of scurvy and the oxides + histamine + toxins cascade. Klenner documented numerous case histories of dramatic recovery from near death toxic shock by injections of AA several times per day, supplemented with several grams orally every one to two hours round the clock for several days to two weeks until recovery. See AA kinetics.
A Well-Documented Analysis of 351 Statin Case Histories: Long-tail
statistics in Drug Adverse Event Report System.
Adverse Events of
Statins - An Informal Internet-based Study The whole study is on the web as a PDF.
This is a well-documented analysis of a
body of 351 case histories that show similar patterns of pathological
conditions.
Abstract:
This report was the result of gathering and collating information
from self-reported accounts of adverse reactions to HMG-CoA reductase
inhibitors.
The information was gathered from 351 patients who had signed an
e-petition that will be sent to the World Health Organization.
Every patient (351) reported adverse reactions to statins and:
The respondents’ complaints about symptoms were often localized
to one or two limbs or several digits. Report numbers: muscle spasm/cramp/
fasciculation (30); neuropathy (24); parasthesia (16); visual disturbance (12);
neuralgia (11); neurological damage (9); Slurred speech (8); auditory
disturbance (7); Tremor (3); dysphagia (1);.
6
of 351 deaths
17
of
351 near death
18
of
351 ALS symptoms induced
29 of 351 serious neurodegenerative disorders
40
of 351 mobility issues/problems
295 of 351 myopathy symptoms
Other
websites have collected over 14,000 adverse cases.
Estimated
15 million patients treated. Rate of
harm is .1% or likely several times higher than these web results.
The update concluded by stating that there was “sufficient
evidence to support a causal relationship” between statins and the
newly acknowledged adverse reactions.
In
the UK, the information was related to the latest instruction from the Medical
& Health Products Regulatory Agency where adjustments to the patient
information leaflet for statins and a change in the
information given to patients by their treating clinicians is now mandatory.
http://www.medications.com/lipitor/lipitor-side-effects
“I am a 56-year-old male who has been relatively good health. I have been taking Lipitor 10 mg three times a week for approximately 8 years with excellent cholesterol results.
I have been noticing more lower-leg discomfort/pain over the last couple years, and particularly numbness/tingling in my feet this past year. I had been running 12-16 miles each week up to the lst year and have had to cut back on this because of the heavy sensation in lower legs and also some osteoarthritis which has been developing over the last 20 years.
My Lipitor dose was increased to 10 mg daily last year after my brother died suddenly from a cardiac event and my family history suggested it might be warranted to increase the dose, but after 3 months I couldn't stand the extra pain, so cut back to 3 days a week.
I still am bothered with these symptoms but not to the same degree. Should I
stop all together?”
Reply Dave847 - Adverse
Side Effects of Statin Cholesterol Lowering Drugs The following headlines from
HEALTHFREEDOMNEWS reveal the many little-known side effects of the artificial
statin drugs, some of which are required to be reported in Canadian statin drug
ads, but not the U.S. versions.
[From:
CoQ10 and Statins: The Vitamin C Connection by Owen R.
Fonorow, 2003]
Statin Cholesterol Lowering
Drugs have the following characteristics:
1.
They deplete the ubiquinone
(vitamin-like) Coenzyme Q10 causing cardiomyopathy and heart failure.
2.
They change, weaken, damage,
or destroy muscle (depending on dose and concomitant use of other drugs).
3.
They do not slow
atherosclerosis. (plaques will increase)
4.
They make atherosclerosis
worse (scurvy is induced).
5.
They increase AA burn-rate;
AA intake needs are greatly increased.
6.
They increase allergic
sensitivities.
7.
They complicate COPD,
chronic dry cough.
8.
They induce sudden total
memory loss.
9.
They increase eye cataract
risk. (lenses of eyes has 20x concentration of AA, but glycemic condition
blocks uptake into cells)
10.
They suppress immune
function. By interfering with immune
cell mitochondria energy pathways.
11.
They are linked to cancer.
12. They
have been linked for ten years with Rhabdomyolysis and Myoglobinuria.
13.
They have been linked with
elevated transaminase (indicator of liver and kidney damage).
14.
They are linked to nerve
damage. Cholesterol starvation,
oxidation, and energy pathway dysfunctions.
15.
They slow mental functions
and decrease focus.
16.
They induce muscle pain, and
cause muscles to atrophy. This applies to heart, reducing oxygen flow. Heme A
is reduced causing less transport per blood cell.
17.
They do not extend life.
18.
They increase serum Lp(a)
concentrations (increasing odds of heart attack or stroke up to 70%).
19.
They reduce left ventricular
function.
20.
They elevate the lactate to
pyruvate ratio.
21.
They enhance LDL cholesterol
oxidation. Result is toxic cholesterol. Need more AA to detoxify.
22.
They interfere with any function
that depends on cholesterol or CoQ10 or vitamin C. (e.g., sex hormone
production, hair growth, sleep, or proper brain and nerve function, nerve
replacement and muscle cell growth/replacement)
23.
They are prescribed to 13
million (in the U.S., 25 million worldwide) creating a $20 billion market.
24.
They will cause 65,000
predicted new myopathies per year. [USA?/World?]
Defenses against Statins
side effects: AA and CoQ10 and Lysine
Supplemental Vitamins C, E and CoQ10 are
completely nontoxic and would lessen or eliminate most of these statin-induced
effects.
However if enough of the right kind of
cholesterol is not maintained, the neural effects will be neuropathies and
myelin sheath dysfunctions. Saturated fats are precursors to making
cholesterol, so Lauric, Palmitic, Capric, Caproic, Caprylic, Butyric acids are
needed in small quantities as molecular feed molecules for hormones.
More headlines illustrate
the health benefits of Vitamin C: from bolenreport.com
1.
Harvard: Vitamin C Only 1 of
880 Substances to Regenerate Heart Muscle From Stem Cells.
2.
Fifteen-Year Harvard Study
of 85,000 Finds Single Vitamin C Pill Reduces Heart Disease Almost 30%.
3.
Linus Pauling Angina and
Heart myopathy reversed: With Vitamin C+Lysine+Proline+vitamins+CoQ10
4.
The Risk Of Stroke Was 70%
Higher Among Those in the Lowest Quartile for Serum Vitamin C Than Among Those
in the Highest.
5.
Vitamin C heals
atherosclerosis.
6.
Vitamin C Inhibits Lipid
Oxidation in Human HDL.
7.
More Vitamin C as Pills
Reduce Cataracts by 77%.
8.
High-Dose Vitamin C
Completely Prevented Drug-Induced Amnesia in Mice.
9.
Carnitine, Its Building
Blocks Vitamin C and Lysine, Increase Muscle Strength.
10. Matthias
Rath Claims Cancer Halted With Vitamin C+Lysine+Proline and EGCG (Green Tea
Extract).
11. Vitamin
C Boosts Immune System in as Little as 5 Hours (NIH).
12. Vitamin
C Pills Extend Life 6-Years (USC).
13. Vitamin
C (and Lysine) Halt Atherosclerosis
14. IV
Vitamin C Reverses Endothelial Dysfunction.
15. Vitamin
C neutralizes many toxins, including toxic shock.
16. Vitamin
C acts as an antihistamine in suppressing asthma and allergies.
17. Vitamin
C neutralizes oxides ROS & NOS
18. Vitamin
C increases blood oxygen transport.
19. Vitamin
C helps mitochondria to recover from toxic dysfunctions
20. Vitamin
C chelates metals, especially toxic aluminum an adjuvant in vaccines.
21. Vitamin
C - New Treatment for Osteoporosis.
22. Vitamin
C Can:
·
Prevent the Deterioration of
Heart Blood Vessels, Completely; and
·
Cure Even Large Aortic
Aneurysms (with L-lysine & L-proline) Without Surgery.
From: CoQ10 and Statins: The Vitamin C Connection by Owen R. Fonorow � 2003
Fonorow’s Conclusions [with our comments]
·
Apparently a $20 billion market
has blinded some scientists. Merck and other pharmaceutical companies have
known about the CoQ10 biosynthesis issue for more than a decade. (Few medical
doctors in the U.S. are aware of this problem, or how serious it can be without
the proper nutritional changes)
·
No theory exists to justify
the use of statin drugs. This author has seen no data or evidence that
demonstrates any real health benefit for statin drug use that overcomes the
proven detriment of hampering the production of CoQ10.
·
One has to ask how the FDA
approved the existing claims for the statin drugs. Apparently the dosage of a
statin is important. [Too high a dosage
causes significant harm. The biochemistry of the harm is documented but ignored
by the regulators, who rely on outdated and flawed low dosage statistical
reports]
·
[Dosages have increased from
the low levels of the original safety testing.
Current dosages have much increased harmful effects, because they lower
CoQ10 blood levels so much, and lead to increased ROS&NOS levels in the
mitochondria, DNA damage, mitochondrial dysfunction]
·
At lower dosages, the
"bad" effects are reduced so that the mortality curves between the
control and statin groups are similar. The studies rarely try to quantify
muscular aches and pains and, instead, usually focus on lowered cholesterol as
the end-point.
·
Ergo, if the drug lowers
cholesterol, beneficial effects on heart patients are assumed.
·
[Harmful effects are
dismissed. Like: without the antioxidants, oxides of the lipids form and
cholesterol oxides are neurotoxins]
According to Dr. Langsjoen, See Introduction
to CoQ10 UofWashington:
Ely Langsjoen "Introduction to CoQ10"
·
In my practice of 17 years
in Tyler, Texas, I have seen a frightening increase in heart failure
secondary to statin usage: statin cardiomyopathy.
·
Over the past five years,
statins have become more potent, have been prescribed in higher dosages, and
have been used with reckless abandon in the elderly and in patients with [near]
normal cholesterol levels. [Without
CoQ10 & vitamin C supplementation]
·
We are in the midst of a
congestive heart failure epidemic in the U.S., with a dramatic increase over
the past decade. [Statins do not work]
·
Are we causing this epidemic
through our zealous use of statins? In large part, I think the answer is yes.
PHL Postulation:
No human who consistently
consumes 10,000 mg or more Ascorbic Acid (vitamin C each day) and 300 mg or
more of ubiquinone (CoQ10) daily has heart disease. [Add L-Lysine and L-Proline
for more effectiveness according to Pauling and Rath]
PHL Predictions:
·
Studies that purport to show
that statins benefit heart patients either have mischaracterized the data or,
eventually, will be shown to be fraudulent, marketing propaganda. [Look into the pseudo science of Dr
Ancel Keys, a discredited fraudster.]
·
We defy any researcher to
find a contrary example to our postulation, and we stand by the prediction.
·
Cardiologists, as a rule,
are highly trained professionals, yet they are being duped by drug company
efforts to expand markets. They love these statin drugs, and why not? Patients
keep coming back.
PHL
Conclusions:
·
Nonetheless, we find it
unconscionable that editors of mainstream medical journals, along with
representatives of the U. S. government and the news media, continue to hide
the explosive research results on vitamin C and CoQ10 from U.S. doctors.
·
We are now in a position to witness the unfolding of the greatest
medical tragedy of all time—never before in history has the medical
establishment knowingly created a life threatening nutrient deficiency in
millions of otherwise healthy people.
·
Disregarding malpractice,
the continuance of ignoring vitamin C and CoQ10, while marketing and
prescribing statin drugs for heart patients is criminal.
--Peter H. Langsjoen, MD
Our Conclusion: The medical cost
explosion is from not using orthomolecular medicine and nutrition.
Drug companies failed to educate doctors
in the proper combined statin & CoQ10 & Ascorbic Acid dosages,
resulting in a lot of uncontrolled ROS and NOS with side effects, cholesterol
poisoning by oxidation, causing mitochondrial dysfunction, immune T-cell
dysfunctions, and increased susceptibility to vaccine side effects causing
neurological harm. Since AA is
depleted, scurvy threshold is worsened and aging is speeded up.
Except
for the Medicare costs of treating the increased symptoms, the billions of
dollars in savings in the SSI retirement costs due to earlier deaths would be
welcome to a government that is unable or unwilling to repay the tax dollars
borrowed from the SSI trust fund. However this early death savings is more than offset by costs from the harm
from vaccine caused disabilities caused by not integrating AA intake with
vaccinations, causing excess costs in the SSI long term disability trust fund
due to the autism epidemic.
Now the CDC and the FDA have recognized
that the combination of mitochondrial dysfunction (or existing ROS/NOS) and
some vaccines (Flu, HiB, DPT, MMR, HPV) can lead to Autism and ASD neural
atrophy. For older persons this
dysfunction shows as fatigue. For young
children it shows as fussiness, and also many of the symptoms of ASD. The Flu
vaccine can cause an adverse reaction when the accumulated microbial parasite
load is high enough.
The FDA has a table on their website
that indicates that vaccination should not be administered if the patient feels
unwell, or if various immune cells are compromised. The table remains unused because there is no practical way
suggested to quickly test for this.
Suggestion: Find a test that would work and use it. SED rate? AA blood level? Histamine level? ROS/NOS
levels?
Too many clinicians do not understand
how critical the scurvy state is to health and how quickly (1-2 hours)
borderline AA levels can become too low and critical to survival. They assume
scurvy does not exist today but cannot recognize it.
The depleted AA state coincident with
vaccination causes adverse events that are well documented elsewhere on the
web. See Kalokerinos, Klenner, and Cathcart, Stone.
The pharmacokinetics (1/2 hour, blood
serum AA half-life is remarkable, almost unbelievable. But its consequences,
when understood, lead to validation of a new low cost, unprofitable treatment
modality (AA, CoQ10, Lysine, Proline) that is extremely effective.
So effective that it is considered a
threat to the entire medical delivery system. Causing its use to be blocked
for over 50 years by the medical gatekeepers. It is up to the smart ones to find a way to make it generally
available in all its modalities, not to suppress it.
The government no longer can afford the
costs of punishing its citizens (both old and young) by blocking this nutrition modality. Read and heed the wise words of John Ely. See References Above.
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Copyright
June 1, 2012
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by KF and KM Poehlmann