Mycoplasmas and Ureaplasmas: Strains, Drug Susceptibilities and Resistance (1988-1994)  from  Baseman & Tully, Poulin et al, and Wates et al

 

Mycoplasma    Strain                  

 Susceptibility to

 Resistant to

M. pneumoniae 14 strains

Erythromycin, tetracycline, doxycycline

 

  found in respiratory/

oxytetracycline

 

  urogenital tracts

clarithromycin A63075

 

 & synovial fluid

temafloxacin, difloxacin, ciprofloxacin

                                                                       

 

 

 

U. urealyticum       28 strain

 found in  

temafloxacin,

difloxacin (somewhat)

 erythromycin (5 strains)

clarithromycin A63075 

   urogenital/

   respiratory tract &

   synovial fluid

ciprofloxacin (some strains)

ofloxacin

doxycycline, tetracycline                           

Tetracycline some strains

(Baseman & Tully)                   

 

 

 

M. hominis    20 strains       

found in urogenital/

respiratory tract                                                  

tetracycline, doxycycline, clindamycin

temafloxacin, difloxacin

erythromycin (all strains) clarithromycin A63075 tetracycline some strains

(Baseman & Tully)

                     

 

 

M. fermentans(incognitis)

var. incognitis        NIH 713-001-084

found in

urogenital tract & synovial fluid

tetracycline, doxycycline,

clindamycin

erythromycin 

 

 

 

 

M. penetrans

GTU 54-6A1

Erythromycin, tetracycline, doxycycline,

Clindamycin, zithromycin, clarithromycin, ofloxacin

                                                                           

       

   

 

M. purim  70-159

Found in urogenital tract                               

tetracycline, doxycycline, clindamycin

zithromycin, clarithromycin, ofloxacin    

                                                                     

 

M. orale

found in the (mouth) & respiratory tract

 

 

M. salivarium

found in the (mouth,) respiratory & urogenital tract

 

 

M. hyorhinis

found in synovial fluid

 

 

M. bucale

found in respiratory tract

 

 

M. arthritidis

found in synovial fluid

 

 

 

Table from Road Back Foundation at

http://www.roadback.org/index.cfm?fuseaction=studies.display&display_id=184

 

List Found: Cassell & Cole, name of article,NEJM ,304:2, 1981,

 

Drugs Found:

Waites, Cassell, Canupp, Fernandes, In Vitro Susceptibilities of Mycoplasmas and Ureaplasmas of New Macrolides and Aryl-Fluoroquniolones, Antimicrobial Agents and   Chemotherapy, 32:10, Oct. 1988,      

 

Baseman & Tully, Mycoplasmas, Sophisticated, Reemerging and Burdened by Their Notoriety, Emerging Infect Dis, 3:1.

 

Poulin, Perkins, Kundsin, Antibiotic Susceptibilities of AIDS-Associated Mycoplasmas, J of Clin Microbiol, 32:4, 1994.

 

 

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