Exo-toxins are produced and emitted by
bacteria in both acute and chronic infections.
Microbes produce endo-toxins
when they die. Body cells that die
also produce toxins. Toxins act to cause anti-oxidants to lose one or more
electrons and toxins become deactivated in part by this action. The
anti-oxidant AA converts to oxidant DHA and must be excreted or it will kill
body cells. Allergens and other immune cells, recognizing infections, cause
immune mast cells to produce products that kill microbes and body cells, that
oxidize cholesterol and lipids, and that produce more toxins. Oxidation of lipids make neurotoxins. Peroxides rapidly deplete free vitamin
C. Intake of enough antioxidant AA stops this toxin/oxidation
cascade.
Vitamin C is ascorbic acid (AA). It is present and
stored in the body as ascorbate. It has
three forms: anti-oxidant, single-oxidized and double oxidized. The double oxidized form is dehydroxy
ascorbic acid. (DHA, or sometimes, DHAA)
AA takes part in many life-critical chemical pathways, where it is
recycled.
AA is an essential molecule; we must eat it; we do
not make it. We can store a limited amount of it, but when that amount is
depleted by ever increasing toxins, we get very sick. Indeed, the sickness, pain, itching, irritation, inflammation
that we feel are the feelings of AA depletion.
If we quickly replace enough AA, we immediately feel better, until the
toxins deplete that new AA, and we need to intake more.
AA rapidly converts to DHA, systemically, in the
presence of reactive oxidative stress (ROS), of all toxin overloads, of vaccine
induced stress, of chronic and acute infections, of antibiotic produced
endo-toxemia, of Jarish Herxheimer reactions, of snake and insect venoms, of
environmental toxin/allergen intake, of smoke inhalation and carbon monoxide
poisoning, of sinus headache inflammation, of sunburn and heatstroke toxins,
etc. See: Dr.
Levy's AA Antitoxin Chapter 3
When free AA is depleted, and the amount of toxins is still large compared to the amount of systemic AA, most free AA converts to DHA, and the life-giving chemical pathways dependent on AA are blocked. Vital chemical reactions stop. The ratio of AA/DHA nears unity or below, histamine is produced by immune mast cells and blood levels of histamine rise exponentially. Histamine poisons the system, and the blood vessels start to leak blood and other fluids. Extreme allergic respiratory tract distress reactions occur, itching, pain and inflammation can and do result.
As
a last life saving measure, an emergency injection of adrenaline can cause
release of a few (~5 grams) of AA from the adrenal glands. When that is
converted to DHA the AA/DHA ratio again
plummets. If no supplemental AA is
provided by injection, anaphylaxis and death can result. The adrenaline injection would not be needed
if AA was supplied IV in large enough (multi tens of grams per hour)
quantities. Along with a need for an adrenaline shot, goes the need for
repeated supplemental AA intake. See: How
Vitamin C Works
An
autoimmune cascade of toxins is the result of AA/DHA <1 and declining.
DHA is an oxidant and must be excreted, requiring
water intake, and free flow of urinary functions.
High intake of supplementary anti-oxidants is
needed. IV Glutathione intake can act to reduce the DHA, but this is not
usually provided. Frequently-repeated
supplemental multiple (2-3) gram quantities of AA intake are an economical way
to improve and maintain the high values of the AA to DHA ratio and improve the
chemical pathways operation. This
applies both during emergency crisis and to speed recovery. Additional antioxidants like CoQ10, vitamin
A and vitamin E should also be supplemented during recovery.
If the AA/DHA ratio is in the range 4-10 vitality is
good and toxemia risks are low.
However, the blood half-lifetime of AA is ½ hour. So with systemic
toxemia, the AA/DHA ratio can change dynamically in just a few minutes or
hours. After 6 hours the AA level can
deplete to ½ to the 12th power, i.e. 1/4000th of the
starting value, to a negligible, not protective amount. Oral AA intake, gut-to-blood
transfer-efficiency is less than 15% for water soluble AA.
Low systemic AA, chronic respiratory/gut infections,
endotoxins, vaccinations, and low AA/DHA ratio, all acting together, have been
identified as causes of sudden infant death syndrome (SIDS), shaken baby syndrome (SBS), asthmatic
allergic reactions, COPD exacerbations,
and anaphylaxis symptoms which can include congestive heart dysfunctions. See Baby Yurkos
Autopsy
Forms of AA intake are Oral, parenteral (injection)
and Intra-Venous (IV) sodium ascorbate.
Oral (water soluble) AA can be in the form of AA,
sodium ascorbate, calcium ascorbate (ester-C), magnesium ascorbate, and
ascorbyl palmitate. Health supplement
suppliers market these forms.
Another form of oral-intake AA, with superior
pharmacokinetics and effectiveness, is Liposomal
Vitamin C. Liposomal AA (L-AA)
is AA nano-encapsulated (homogenized) with phospholipid lecithin. Its transport from gut to blood is more than
5 times better than for water soluble AA. Also, L-AA crosses the blood brain
barrier better.
L-AA has an affinity (attraction) for microbes
(bacteria and viruses) and body cells with lipid envelopes. L-AA delivers AA
7-11 times more effectively than water-soluble forms of AA to the cells, where the
AA acts to kill microbes and microbe invaded cells.
L-AA thus can be taken orally, and produce
pharmacokinetic concentrations equivalent or better than IV therapy,
conveniently and at low cost. L-AA is available on Amazon.com. Users
reviews of L-AA are found at Amazon.com and at the Vitamin C
Foundation.
IV AA and parenteral AA is usually sodium ascorbate,
sometimes with a small fraction of magnesium ascorbate and other critical
electrolytes. Magnesium helps reduce
the occurrences of heart fibrillations, because magnesium deficiency is
associated with higher fibrillation risk. Orthomolecular MDs are familiar with
IV AA administration. See Papers by
Drs. Klenner and Cathcart.
Multi
Toxemia Case History:
COPD Respiratory Polymicrobial Infections; Treatment is
symptomatic. Responds positively to AA
in levels over 8 grams per day 4-6x/d of 2 grams.
UTI Blockage, Infection & Toxemia: failure to void, always a
full bladder, incontinence; Constant/recurring UTI infections. Urologist failed to see patient because his
building lost electric power and facility was blacked out. Ultrasound room had
power and full bladder was confirmed. Patient has had great difficulty
obtaining urine sample of any quantity for period of many weeks. Cause of UTI blockage is unknown, blockage
location below bladder. Hysterectomy?
Structural degeneration of supporting cartilage resulting from Cipro? Stones?
Effects of blockage on kidneys? Unknown, but worrisome. Never been
catheterized. Should she be?
Periodically?
Treatment of UTI with Cipro causing: Microbes die, Endotoxins
release, Systemic Toxemia, AA oxidized
to DHA, AA/DHA ratio shifts to critical range.
Extreme pain (plantar fasciitis) relieved overnight
by higher afternoon and evening AA intake.
After oral Cipro: Extreme systemic muscle pains,
Remedy for pains is 2-3 grams AA every 2-3 hours. Pain relief within a few hours, permanent muscle pain relief, if
AA dosage is repeatedly kept high enough.
Cipro causes blockage of cartilage protein making
and muscle regeneration. Cipro blocks DNA unzipping enzyme needed to transpose
codes to RNA as part of protein making pathways.
First hospital visit with respiratory episode: AA
intake was not given on late evening and at retiring, but vital signs were very
good before retiring.
Next morning after ~10 hours of no AA intake no AA
on arising: AA blood half lifetime is ½
hour. This is ½ to 20th power depletion of blood AA. ~1/500,000th.
Extreme breathing (shortness of breath) episode and
chest pains. Heart
Attack. Temp 99.2 degrees, some heart irregularities. Fibrillations in
ER. Symptoms overlap some of those of
anaphylaxis (AA depletion)
First-Aid 3 grams AA and 50 mg CoQ10, Then emergency
room, IV Cipro, concurrent AA given by family with Drs’ permission. Other IV antibiotics not Cipro administered.
On return after 7-day hospital stay, continued 2
grams AA every 2-3 hours, at bedtime and on arising. Vitality improving each day.
After 7 more days seems not to need much oxygen at all.
Bladder remains blocked; how and why
undiagnosed. Waiting on new referral to
see urologist.
Because of recurring bouts of toxemia need to find,
diagnose and fix cause of urinary blockage.
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